Hi Kai Bangcola,

Yes,

            For this you have to create/check the material status in material master.

Transaction: OMS4

           Here you select option "B for purchasing" and all other blank., this settings will block the material for further procurement & allows Inventory activities like GI, GR etc.

For just blocking,

Transaction : MM02,

         Basic Data: X-Plant Material Status--> Option-01 [Blocked for Procurement]

Also refer, the note:

Material master deletion flag and blocking

Regards

Mani